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To explode metaphorically; to become very angry.

When the boss came to know about the scheme, he went off, shouting and throwing everything away.

Additional definitions for 'go off':

go offTo explode.
go offTo begin clanging or making noise.
go offTo depart; to leave.
go offTo putrefy or become inedible.
go offTo like less.
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"go off." Phrases.net. STANDS4 LLC, 2017. Web. 20 Nov. 2017. <http://www.phrases.net/phrase/go-off_661>.

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