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To become successful, to flourish.

The business has really taken off this year and has made quite a profit.

Additional definitions for 'take off':

take offTo remove.
take offTo imitate, often in a satirical manner.
take offTo leave the ground and begin flight; to ascend into the air.
take offTo depart.
take offTo quantify.
take offTo absent oneself from work or other responsibility, especially with permission.
take offTo leave unexpectedly, blow the joint, leave in a huff, run out, evacuate, disband, abandon, rush away, fly the coop, jump the rails, jump the gun.
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"take off." Phrases.net. STANDS4 LLC, 2017. Web. 20 Oct. 2017. <http://www.phrases.net/phrase/take-off_1545>.

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