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To behave in a disruptive manner.

I seen old Flint in the corner there, behind you; as plain as print, I seen him; and if I get the horrors, I'm a man that has lived rough, and I'll raise Cain. - Treasure Island, Robert Louis Stevenson.

Additional definitions for 'raise cain':

raise cainTo cause trouble.
raise cainThe children tend to 'raise cain' if they can't play ball after supper.
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"raise cain." Phrases.net. STANDS4 LLC, 2017. Web. 25 Nov. 2017. <http://www.phrases.net/phrase/raise-cain_6379>.

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