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Disoriented; not thinking clearly.

Having the flu all week left me pretty well out of it.

Additional definitions for 'out of it':

out of itDrunk.
out of itNot participating in some trend or group.
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"out of it." Phrases.net. STANDS4 LLC, 2017. Web. 21 Nov. 2017. <http://www.phrases.net/phrase/out-of-it_5895>.

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