To ruin; wreck; mess up; screw up; sometimes as a bowdlerized substitution for f** up.
I'm not letting him use my computer again; he always jacks it up.
Additional definitions for 'jack up':
|jack up||To raise, hoist, or lift a thing using a jack, or similar means.|
|jack up||To raise, increase, or accelerate; often said of prices, fees, or rates. See also jack up the price.|
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